LAMA5, laminin subunit alpha 5, 3911

N. diseases: 56; N. variants: 9
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2236521
rs2236521
Entrez Id: 3911
Gene Symbol: LAMA5
LAMA5
CUI: C0017654
Disease:
Glomerular Filtration Rate 		A 0.700 GeneticVariation GWASCAT A catalog of genetic loci associated with kidney function from analyses of a million individuals. 31152163 2019
dbSNP: rs1741640
rs1741640
Entrez Id: 3911
Gene Symbol: LAMA5
LAMA5
CUI: C2677123
Disease:
COLORECTAL CANCER, SUSCEPTIBILITY TO, 3 		C 0.700 GeneticVariation GWASCAT Association analyses identify 31 new risk loci for colorectal cancer susceptibility. 31089142 2019
dbSNP: rs1741640
rs1741640
Entrez Id: 3911
Gene Symbol: LAMA5
LAMA5
CUI: C2675481
Disease:
COLORECTAL CANCER, SUSCEPTIBILITY TO, 10 		C 0.700 GeneticVariation GWASCAT Association analyses identify 31 new risk loci for colorectal cancer susceptibility. 31089142 2019
dbSNP: rs1741640
rs1741640
Entrez Id: 3911
Gene Symbol: LAMA5
LAMA5
CUI: C0009402
Disease:
Colorectal Carcinoma 		C 0.700 GeneticVariation GWASCAT Association analyses identify 31 new risk loci for colorectal cancer susceptibility. 31089142 2019
dbSNP: rs1741640
rs1741640
Entrez Id: 3911
Gene Symbol: LAMA5
LAMA5
CUI: C1837315
Disease:
COLORECTAL CANCER, SUSCEPTIBILITY TO, 1 		C 0.700 GeneticVariation GWASCAT Association analyses identify 31 new risk loci for colorectal cancer susceptibility. 31089142 2019
dbSNP: rs1741640
rs1741640
Entrez Id: 3911
Gene Symbol: LAMA5
LAMA5
CUI: C0346629
Disease:
Malignant neoplasm of large intestine 		C 0.700 GeneticVariation GWASCAT Association analyses identify 31 new risk loci for colorectal cancer susceptibility. 31089142 2019
dbSNP: rs1741640
rs1741640
Entrez Id: 3911
Gene Symbol: LAMA5
LAMA5
CUI: C0009404
Disease:
Colorectal Neoplasms 		C 0.700 GeneticVariation GWASCAT Association analyses identify 31 new risk loci for colorectal cancer susceptibility. 31089142 2019
dbSNP: rs1741640
rs1741640
Entrez Id: 3911
Gene Symbol: LAMA5
LAMA5
CUI: C1319315
Disease:
Adenocarcinoma of large intestine 		C 0.700 GeneticVariation GWASCAT Association analyses identify 31 new risk loci for colorectal cancer susceptibility. 31089142 2019
dbSNP: rs1741640
rs1741640
Entrez Id: 3911
Gene Symbol: LAMA5
LAMA5
CUI: C0007102
Disease:
Malignant tumor of colon 		C 0.700 GeneticVariation GWASCAT Association analyses identify 31 new risk loci for colorectal cancer susceptibility. 31089142 2019
dbSNP: rs1741640
rs1741640
Entrez Id: 3911
Gene Symbol: LAMA5
LAMA5
CUI: C3554460
Disease:
COLORECTAL CANCER, SUSCEPTIBILITY TO, 12 		C 0.700 GeneticVariation GWASCAT Association analyses identify 31 new risk loci for colorectal cancer susceptibility. 31089142 2019
dbSNP: rs1741640
rs1741640
Entrez Id: 3911
Gene Symbol: LAMA5
LAMA5
CUI: C0007102
Disease:
Malignant tumor of colon 		C 0.700 GeneticVariation GWASCAT Discovery of common and rare genetic risk variants for colorectal cancer. 30510241 2019
dbSNP: rs1741640
rs1741640
Entrez Id: 3911
Gene Symbol: LAMA5
LAMA5
CUI: C1837315
Disease:
COLORECTAL CANCER, SUSCEPTIBILITY TO, 1 		C 0.700 GeneticVariation GWASCAT Discovery of common and rare genetic risk variants for colorectal cancer. 30510241 2019
dbSNP: rs1741640
rs1741640
Entrez Id: 3911
Gene Symbol: LAMA5
LAMA5
CUI: C0346629
Disease:
Malignant neoplasm of large intestine 		C 0.700 GeneticVariation GWASCAT Discovery of common and rare genetic risk variants for colorectal cancer. 30510241 2019
dbSNP: rs1741640
rs1741640
Entrez Id: 3911
Gene Symbol: LAMA5
LAMA5
CUI: C1319315
Disease:
Adenocarcinoma of large intestine 		C 0.700 GeneticVariation GWASCAT Discovery of common and rare genetic risk variants for colorectal cancer. 30510241 2019
dbSNP: rs1741640
rs1741640
Entrez Id: 3911
Gene Symbol: LAMA5
LAMA5
CUI: C0009402
Disease:
Colorectal Carcinoma 		C 0.700 GeneticVariation GWASCAT Discovery of common and rare genetic risk variants for colorectal cancer. 30510241 2019
dbSNP: rs1741640
rs1741640
Entrez Id: 3911
Gene Symbol: LAMA5
LAMA5
CUI: C0009404
Disease:
Colorectal Neoplasms 		C 0.700 GeneticVariation GWASCAT Discovery of common and rare genetic risk variants for colorectal cancer. 30510241 2019
dbSNP: rs1741640
rs1741640
Entrez Id: 3911
Gene Symbol: LAMA5
LAMA5
CUI: C3554460
Disease:
COLORECTAL CANCER, SUSCEPTIBILITY TO, 12 		C 0.700 GeneticVariation GWASCAT Discovery of common and rare genetic risk variants for colorectal cancer. 30510241 2019
dbSNP: rs1741640
rs1741640
Entrez Id: 3911
Gene Symbol: LAMA5
LAMA5
CUI: C2675481
Disease:
COLORECTAL CANCER, SUSCEPTIBILITY TO, 10 		C 0.700 GeneticVariation GWASCAT Discovery of common and rare genetic risk variants for colorectal cancer. 30510241 2019
dbSNP: rs1741640
rs1741640
Entrez Id: 3911
Gene Symbol: LAMA5
LAMA5
CUI: C2677123
Disease:
COLORECTAL CANCER, SUSCEPTIBILITY TO, 3 		C 0.700 GeneticVariation GWASCAT Discovery of common and rare genetic risk variants for colorectal cancer. 30510241 2019
dbSNP: rs1741640
rs1741640
Entrez Id: 3911
Gene Symbol: LAMA5
LAMA5
CUI: C1302401
Disease:
Adenoma of large intestine 		C 0.700 GeneticVariation GWASCAT Discovery of common and rare genetic risk variants for colorectal cancer. 30510241 2019
dbSNP: rs62199218
rs62199218
Entrez Id: 3911
Gene Symbol: LAMA5
LAMA5
CUI: C2985280
Disease:
Blood Protein Measurement 		A 0.700 GeneticVariation GWASCAT Genomic atlas of the human plasma proteome. 29875488 2018
dbSNP: rs4925386
rs4925386
Entrez Id: 3911
Gene Symbol: LAMA5
LAMA5
CUI: C0009402
Disease:
Colorectal Carcinoma 		0.830 GeneticVariation BEFREE For SNPs on 18q21 (rs12953717 and rs4464148) and 20q13 (rs4925386), alleles that correlate with higher risk for the development of CRC are associated with shorter disease free survival (DFS). 29119627 2018
dbSNP: rs369572769
rs369572769
Entrez Id: 3911
Gene Symbol: LAMA5
LAMA5
CUI: C0020676
Disease:
Hypothyroidism 		0.010 GeneticVariation BEFREE The heterozygous <i>LAMA5</i> mutation c.9418G>A (p.V3140M) was associated with skin anomalies, impaired scarring, night blindness, muscle weakness, osteoarthritis, joint and internal organs ligaments laxity, malabsorption syndrome and hypothyroidism. 28735299 2017
dbSNP: rs369572769
rs369572769
Entrez Id: 3911
Gene Symbol: LAMA5
LAMA5
CUI: C0028077
Disease:
Nyctalopia 		0.010 GeneticVariation BEFREE The heterozygous <i>LAMA5</i> mutation c.9418G>A (p.V3140M) was associated with skin anomalies, impaired scarring, night blindness, muscle weakness, osteoarthritis, joint and internal organs ligaments laxity, malabsorption syndrome and hypothyroidism. 28735299 2017
dbSNP: rs4925386
rs4925386
Entrez Id: 3911
Gene Symbol: LAMA5
LAMA5
CUI: C0009402
Disease:
Colorectal Carcinoma 		0.830 GeneticVariation BEFREE Notably, two independent meta-analyses of genome-wide association studies found the C-allele of LAMA5 rs4925386-C/T correlated with the risk of colorectal cancer. 26968355 2016